Effects of Long Term Use of Naproxen on the Kidneys

Long term use of naproxen can lead to: renal papillary necrosis-death of the opening area of the collecting ducts that enter the kidney, renal insufficiency-poor regulation of blood pressure and ability to remove waste, and acute renal failure-acute s…

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Long term use of naproxen can lead to: renal papillary necrosis-death of the opening area of the collecting ducts that enter the kidney, renal insufficiency-poor regulation of blood pressure and ability to remove waste, and acute renal failure-acute shutdown in renal function.

 

 

Effects of Long Term Use of Naproxen on the Kidneys

Long term use of naproxen can lead to: renal papillary necrosis-death of the opening area of the collecting ducts that enter the kidney, renal insufficiency-poor regulation of blood pressure and ability to remove waste, and acute renal failure-acute s…

aleve-image

Long term use of naproxen can lead to: renal papillary necrosis-death of the opening area of the collecting ducts that enter the kidney, renal insufficiency-poor regulation of blood pressure and ability to remove waste, and acute renal failure-acute shutdown in renal function.

 

 

Effects of long term use of naproxen on the kidneys

Long term use of naproxen can lead to: renal papillary necrosis-death of the opening area of the collecting ducts that enter the kidney, renal insufficiency-poor regulation of blood pressure and ability to remove waste, and acute renal failure-acute shutdown in renal function.  

Long term use of naproxen can lead to: renal papillary necrosis-death of the opening area of the collecting ducts that enter the kidney, renal insufficiency-poor regulation of blood pressure and ability to remove waste, and acute renal failure-acute shutdown in renal function.

 

Sodium Phosphate’s Effect on the Kidneys

Sodium phosphate is a drug that is typically used as a laxative or bowel prep. That sounds pretty innocuous, but The National Kidney Foundation begs to differ. Oral sodium phosphate can cause acute renal injury because phosphate crystals can accumulate in the kidney and cause a loss of function. In 2009 the FDA recommended that … Continue reading “Sodium Phosphate’s Effect on the Kidneys”

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Sodium phosphate is a drug that is typically used as a laxative or bowel prep. That sounds pretty innocuous, but The National Kidney Foundation begs to differ.

Oral sodium phosphate can cause acute renal injury because phosphate crystals can accumulate in the kidney and cause a loss of function. In 2009 the FDA recommended that manufacturers add a black box warning to drug packaging. Sodium phosphate is available over the counter and a stronger version is available by prescription.

 

“Oral Sodium Phosphate Safety Alerts.” National Kidney Foundation. https://www.kidney.org/atoz/content/oralsodium

 

Acyclovir and the kidneys

Acyclovir is a drug commonly used to help alleviate herpes. It is metabolized in the liver and more than 90% of it gets excreted (unchanged) through the kidneys. It is to be used cautiously in patients who have preexisting renal complications because i…

Acyclovir is a drug commonly used to help alleviate herpes. It is metabolized in the liver and more than 90% of it gets excreted (unchanged) through the kidneys. It is to be used cautiously in patients who have preexisting renal complications because it has side effects of renal failure, crystalluria, hematuria, and renal pain.

Ciprofloxacin

Cyclosporine, also known as Gengraf, Neoral, or SandIMMUNE, is an immunosuppressant that is used for Prevention and treatment of rejection in renal transplants. It also has an unlabeled use of treating steroid-resistant nephrotic syndrome. It performs this by inhibiting normal immune responses, both cellular and humoral, by inhibiting interleukin-, which initiates T-cell activity. It is […]

Cyclosporine, also known as Gengraf, Neoral, or SandIMMUNE, is an immunosuppressant that is used for Prevention and treatment of rejection in renal transplants. It also has an unlabeled use of treating steroid-resistant nephrotic syndrome. It performs this by inhibiting normal immune responses, both cellular and humoral, by inhibiting interleukin-, which initiates T-cell activity. It is available through PO and IV and is metabolized by the liver and excreted in bile with only a small amount is excreted unchanged in urine. Cyclosporine is contraindicated and should cautiously be used in renal impairment. Some major adverse effects regarding the kidneys is diarrhea, vomiting, hyperkalemia, hypomagnesemia, and nephrotoxicity.

Nursing considerations would be to educate patients that some common side effects are nephrotoxicity, increased blood pressure, hand tremors, increased facial and body hair, gingival hyperplasia. Also, it is important instruct the patient to notify their healthcare provider if they experience hematuria, cloudy urine, decrease output, increased frequency, fever, sore throat, tiredness, or abnormal bruising.

 

Alex Gelinas (Furosemide)

The drug I chose is Furosemide (Lasix). The reason I chose this drug is because it commonly occurs in our readings and seems like a common diuretic we come across in the hospital. This diuretic inhibits reabsorption of sodium and chloride from the loop of Henle and distal renal tubule. It increases renal excretion of … Continue reading “Alex Gelinas (Furosemide)”

The drug I chose is Furosemide (Lasix). The reason I chose this drug is because it commonly occurs in our readings and seems like a common diuretic we come across in the hospital. This diuretic inhibits reabsorption of sodium and chloride from the loop of Henle and distal renal tubule. It increases renal excretion of water, sodium, chloride, magnesium, potassium, and calcium. The drug is still effective when impaired renal function is present. 60-67% of the drug is absorbed after oral administration. 

The patient needs to be assessed for skin rash which could be life-threatening. Fluid status needs to be assessed by monitoring I&O’s, edema, lung sounds, skin turgor, and mucous membranes. BP and pulse should also be monitored. In patients with decreased renal function, hearing loss may occur with high-dose IV administration. 

Kenneth Paul Dadacay 2016-09-20 22:49:23

Aspirin is a NSAID drug that is absorbed primarily in the small intestines. This type of drug can affect our kidneys and cause acute, reversible impairment. This occurs because aspirin

Aspirin is a NSAID drug that is absorbed primarily in the small intestines. This type of drug can affect our kidneys and cause acute, reversible impairment. This occurs because aspirin inhibits COX-1, thereby depriving the kidney of prostaglandins needed for normal function.  If a patient experiences a decrease in urine output or a rise in serum creatinine/BUN levels, the patient should discontinue the drug. With that being said, most patients kidney function return back to normal.

Kenneth Paul Dadacay 2016-09-20 22:49:23

Aspirin is a NSAID drug that is absorbed primarily in the small intestines. This type of drug can affect our kidneys and cause acute, reversible impairment. This occurs because aspirin

Aspirin is a NSAID drug that is absorbed primarily in the small intestines. This type of drug can affect our kidneys and cause acute, reversible impairment. This occurs because aspirin inhibits COX-1, thereby depriving the kidney of prostaglandins needed for normal function.  If a patient experiences a decrease in urine output or a rise in serum creatinine/BUN levels, the patient should discontinue the drug. With that being said, most patients kidney function return back to normal.

Kenneth Paul Dadacay 2016-09-20 22:49:23

Aspirin is a NSAID drug that is absorbed primarily in the small intestines. This type of drug can affect our kidneys and cause acute, reversible impairment. This occurs because aspirin

Aspirin is a NSAID drug that is absorbed primarily in the small intestines. This type of drug can affect our kidneys and cause acute, reversible impairment. This occurs because aspirin inhibits COX-1, thereby depriving the kidney of prostaglandins needed for normal function.  If a patient experiences a decrease in urine output or a rise in serum creatinine/BUN levels, the patient should discontinue the drug. With that being said, most patients kidney function return back to normal.

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