Who- Seen mainly in the adult population. It is more prevalent in countries with overcrowding and poor sanitation. Children or young adults acquire the infection at school through poor hygiene, hand-to-hand contact, or other close contact
What- Caused by RNA virus of enterovirus family
When- Incubation period is estimated 2-6 weeks with a mean of approximately 4 weeks. It may be prolonged, lasting 4-8 weeks
Where- Liver and spleen
Why- Fecal-oral route transmission; poor sanitation; person-to-person contact; waterborne; foodborne; Transmission is also possible with oral-anal contact during sex