As we’ve been learning, the kidneys take on a vital role of filtering substances, and electrolytes, and also to help excrete wastes. When asked to think of a drug that affects the kidneys minimally, or extensively, I thought of vancomycin.
Acting as an anti-infective to eliminate bacteria, vancomycin attaches to the bacterial cell wall, and causes death of the cell. It is used when less toxic medications are contraindicated, therefore making it clear that vancomycin is among the toxic drugs to our bodies. One of the adverse reactions it may lead to, is nephrotoxicity, which is a condition that affects renal function. It is important to monitor intake and output during medical therapy, as well as monitoring the urine for a cloudy or pink appearance, which would indicate nephrotoxicity (Skyscape, 2015). Pertinent lab values to check frequently, are BUN levels which may increase with vancomycin, specific gravity of the urine, and complete blood counts. It is extremely important to note that an individual with renal impairment is monitored closely, and that the dosage of vancomycin is reduced as long as the creatinine clearance rate is less than, or equal to 80mL/min (Skyscape, 2015).
References
Skyscape. (2015). Skyscape Medical Resources (Version 2.3.0) [Mobile application software].
The number one thing that brings me true happiness, is traveling. I wish I could do it more often. I also LOVE the beach! Can’t wait to explore the world once I’m a nurse.
