Cyclosporine and its Effects on the Kidney

Cyclosporine is an immunosuppressant drug with major adverse effects on the kidneys. This drug is absorbed in the gastrointestinal tract and widely distributed. After being metabolized by the liver, small bits of it are excreted in urine. Ironically, this nephrotoxic drug is used to prevent rejections of new kidney transplants. Blood levels of this drug must … Continue reading “Cyclosporine and its Effects on the Kidney”

Cyclosporine is an immunosuppressant drug with major adverse effects on the kidneys. This drug is absorbed in the gastrointestinal tract and widely distributed. After being metabolized by the liver, small bits of it are excreted in urine.

Ironically, this nephrotoxic drug is used to prevent rejections of new kidney transplants. Blood levels of this drug must be periodically assessed to ensure that it hasn’t reached toxic levels, and BUN and serum creatinine levels are monitored for kidney damage. Rise in either of these kidney lab values, however, must be further assessed to determine wether the cause is due to kidney damage or rejection of the kidney transplant. Patients who have both renal impairment and rheumatoid arthritis or psoriasis may not receive this drug. Patients who have only renal impairment, or the other two conditions without the renal impairment, may receive this drug, but kidney function must be closely monitored and the dosage may need to be adjusted.

Due to its nephrotoxic effects, patients must be educated on what to report. This includes an increase in blood pressure, hematuria, an increase urinary frequency, decrease in urine output, or cloudy urine.

 

Cyclosporine and its Effects on the Kidney

Cyclosporine is an immunosuppressant drug with major adverse effects on the kidneys. This drug is absorbed in the gastrointestinal tract and widely distributed. After being metabolized by the liver, small bits of it are excreted in urine. Ironically, this nephrotoxic drug is used to prevent rejections of new kidney transplants. Blood levels of this drug must … Continue reading “Cyclosporine and its Effects on the Kidney”

Cyclosporine is an immunosuppressant drug with major adverse effects on the kidneys. This drug is absorbed in the gastrointestinal tract and widely distributed. After being metabolized by the liver, small bits of it are excreted in urine.

Ironically, this nephrotoxic drug is used to prevent rejections of new kidney transplants. Blood levels of this drug must be periodically assessed to ensure that it hasn’t reached toxic levels, and BUN and serum creatinine levels are monitored for kidney damage. Rise in either of these kidney lab values, however, must be further assessed to determine wether the cause is due to kidney damage or rejection of the kidney transplant. Patients who have both renal impairment and rheumatoid arthritis or psoriasis may not receive this drug. Patients who have only renal impairment, or the other two conditions without the renal impairment, may receive this drug, but kidney function must be closely monitored and the dosage may need to be adjusted.

Due to its nephrotoxic effects, patients must be educated on what to report. This includes an increase in blood pressure, hematuria, an increase urinary frequency, decrease in urine output, or cloudy urine.

 

Introduction and Electrolyte Values

Hi Everyone! As you can see from the picture I posted, part of the time that I spend outside of school is with kids – teaching them beginning piano, and then showcasing their progress in a little recital for their family to see. This is a photo taken from a piano recital I held over … Continue reading “Introduction and Electrolyte Values”

dscn2559Hi Everyone!

As you can see from the picture I posted, part of the time that I spend outside of school is with kids – teaching them beginning piano, and then showcasing their progress in a little recital for their family to see. This is a photo taken from a piano recital I held over a year ago.

On a different note, as I’ve been studying my electrolyte values this past week, one electrolyte that I constantly have to go back to and look at is Magnesium (1.8-2.7mg/dL). At first I thought that it would be Chloride or Phosphate that I would have a hard time remembering, because we see those far less frequently than sodium, potassium, or even magnesium. But somehow, I remember those harder values better for that reason. Instead it’s magnesium that I always seem to forget and have to look up again and again. The lab value that I like the most, however, is potassium (3.5-5.0 mEq/L). There are very few numbers to remember and it’s a very common lab value that pops up in patient’s charts. Because it’s so easy for me to remember, potassium lies very dear to my heart.

Introduction and Electrolyte Values

Hi Everyone! As you can see from the picture I posted, part of the time that I spend outside of school is with kids – teaching them beginning piano, and then showcasing their progress in a little recital for their family to see. This is a photo taken from a piano recital I held over … Continue reading “Introduction and Electrolyte Values”

dscn2559Hi Everyone!

As you can see from the picture I posted, part of the time that I spend outside of school is with kids – teaching them beginning piano, and then showcasing their progress in a little recital for their family to see. This is a photo taken from a piano recital I held over a year ago.

On a different note, as I’ve been studying my electrolyte values this past week, one electrolyte that I constantly have to go back to and look at is Magnesium (1.8-2.7mg/dL). At first I thought that it would be Chloride or Phosphate that I would have a hard time remembering, because we see those far less frequently than sodium, potassium, or even magnesium. But somehow, I remember those harder values better for that reason. Instead it’s magnesium that I always seem to forget and have to look up again and again. The lab value that I like the most, however, is potassium (3.5-5.0 mEq/L). There are very few numbers to remember and it’s a very common lab value that pops up in patient’s charts. Because it’s so easy for me to remember, potassium lies very dear to my heart.

Introduction and Electrolyte Values

Hi Everyone! As you can see from the picture I posted, part of the time that I spend outside of school is with kids – teaching them beginning piano, and then showcasing their progress in a little recital for their family to see. This is a photo taken from a piano recital I held over … Continue reading “Introduction and Electrolyte Values”

dscn2559Hi Everyone!

As you can see from the picture I posted, part of the time that I spend outside of school is with kids – teaching them beginning piano, and then showcasing their progress in a little recital for their family to see. This is a photo taken from a piano recital I held over a year ago.

On a different note, as I’ve been studying my electrolyte values this past week, one electrolyte that I constantly have to go back to and look at is Magnesium (1.8-2.7mg/dL). At first I thought that it would be Chloride or Phosphate that I would have a hard time remembering, because we see those far less frequently than sodium, potassium, or even magnesium. But somehow, I remember those harder values better for that reason. Instead it’s magnesium that I always seem to forget and have to look up again and again. The lab value that I like the most, however, is potassium (3.5-5.0 mEq/L). There are very few numbers to remember and it’s a very common lab value that pops up in patient’s charts. Because it’s so easy for me to remember, potassium lies very dear to my heart.

Introduction and Electrolyte Values

Hi Everyone! As you can see from the picture I posted, part of the time that I spend outside of school is with kids – teaching them beginning piano, and then showcasing their progress in a little recital for their family to see. This is a photo taken from a piano recital I held over … Continue reading “Introduction and Electrolyte Values”

dscn2559Hi Everyone!

As you can see from the picture I posted, part of the time that I spend outside of school is with kids – teaching them beginning piano, and then showcasing their progress in a little recital for their family to see. This is a photo taken from a piano recital I held over a year ago.

On a different note, as I’ve been studying my electrolyte values this past week, one electrolyte that I constantly have to go back to and look at is Magnesium (1.8-2.7mg/dL). At first I thought that it would be Chloride or Phosphate that I would have a hard time remembering, because we see those far less frequently than sodium, potassium, or even magnesium. But somehow, I remember those harder values better for that reason. Instead it’s magnesium that I always seem to forget and have to look up again and again. The lab value that I like the most, however, is potassium (3.5-5.0 mEq/L). There are very few numbers to remember and it’s a very common lab value that pops up in patient’s charts. Because it’s so easy for me to remember, potassium lies very dear to my heart.

Hello world!

Welcome to WordPress. This is your first post. Edit or delete it, then start blogging!

Welcome to WordPress. This is your first post. Edit or delete it, then start blogging!

Hello world!

Welcome to WordPress. This is your first post. Edit or delete it, then start blogging!

Welcome to WordPress. This is your first post. Edit or delete it, then start blogging!

Hello world!

Welcome to WordPress. This is your first post. Edit or delete it, then start blogging!

Welcome to WordPress. This is your first post. Edit or delete it, then start blogging!

Hello world!

Welcome to WordPress. This is your first post. Edit or delete it, then start blogging!

Welcome to WordPress. This is your first post. Edit or delete it, then start blogging!

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