Gentamicin has a faster absorption rate when it is given by IM injection, IV administration or by topical agents. It is very poorly absorbed orally. It is excreted through the kidneys at >90% unchanged, which makes it very toxic to the kidneys. Specifically gentamicin causes nephrotoxicity, so if there is renal impairment dose adjustments need to be changed, and blood levels need to be monitored to insure nephrotoxicity is not taking place. Other nursing considerations should be to look out for other nephrotoxic drugs when administering gentamicin, since the incidence may be raised in combination with these types of drugs. Also patients taking this medication should be well hydrated in order to help counteract the nephrotoxic factors.
Gentamicin
Gentamicin has a faster absorption rate when it is given by IM injection, IV administration or by topical agents. It is very poorly absorbed orally. It is excreted through the kidneys at >90% unchanged, which makes it very toxic to the kidneys. Specifically gentamicin causes nephrotoxicity, so if there is renal impairment dose adjustments need […]